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Can cannabis help with my anxiety? In this chapter, we learn what anxiety is, how cannabis can help, and also discover cultivars that may help with this misunderstood condition.
Chapter 7 · 6 min read

Mental health is vastly misunderstood and undertreated by the traditional healthcare system. As legalization and research on cannabis medicine move forward, however, we are seeing people with mood disorders getting relief from cannabis. In fact, in one recent study, 66% of self-reported cannabis use sessions on one app resulted in positive anxiety relief.
But cannabis might not help with everyone’s anxiety. For a minority of consumers, their anxiety actually increases after using it. We’ll learn how to best avoid these situations where our anxiety and paranoia can lead to undesirable experiences. But first, we’ll need to cover what generalized anxiety disorder is.
Those who live with general anxiety disorder are typically characterized by excessive, persistent worry and fear about everyday situations. Symptoms of anxiety include an increased heart rate, rapid breathing, and excessive sweating. All of these physical symptoms can lead to a general feeling of fatigue since these symptoms can be draining on the mind and body.
According to the National Alliance for Mental Illness (NAMI), over 40 million adults have been diagnosed with an anxiety disorder. This is over 19% of the overall population. Most develop symptoms of anxiety before age 21. Perhaps another 10-20 million Americans live with an undiagnosed anxiety condition.

For most of us without an anxiety disorder, feeling stressed or anxious is perfectly normal in stressful situations. Having to perform a task like public speaking or taking an important exam can make anyone feel anxious. Anxiety is only an indicator of an underlying condition when feelings become persistent, obsessive or excessive, all-consuming, and harm our activities of daily living. When anxiety interferes with our lives, it’s time to get help.
Some people living with anxiety conditions may experience episodes of intense anxiety, to the point where they might need hospitalization. These episodes are referred to as panic attacks. Panic attacks often feel like:
Living with a condition like anxiety can be awful. Thankfully, cannabis may provide some relief. Cannabis is thought to help treat mental health issues like anxiety, depression, and PTSD. Anxiety is considered a qualifying condition in most states with medical cannabis programs.
Up until this point, most of the research that has been done regarding studying how cannabis might help treat anxiety has isolated individual cannabinoids, THC and CBD. Researchers at Whistler Therapeutics in British Columbia Canada set out to change this. They documented a promising study, the goal of which was to find cultivars that might be best for helping to relieve symptoms caused by anxiety.
They did this by observing the chemical fingerprint of the plant medicine, a mixture of both terpenes and cannabinoids, which they called a “chemotype”. Even though the study was small scale and had considerable restrictions, the results could lead to more research on cannabis for mental health. For more on cannabinoids, be sure to take a deep dive into our Cannabinoids Guide.

What the expert says...
"Experts speculate that nearly 20 million Americans are living with an undiagnosed anxiety disorder, and even more simply live with normal or subclinical feelings of anxiety."
The results the research team got might help us better understand other studies in the future. What the researchers found were 4 cultivars that they feel will help treat anxiety symptoms and 4 that they recommend avoiding. All four of these have high THC levels, but this is certainly not to say that low-level THC cultivars cannot treat anxiety. Here are the four cultivars the research team came away with.
The researchers found that the terpene terpinolene was prominent in the cultivars that were ineffective in treating anxiety. For whatever reason, this terpene had a negative interaction with patients with anxiety. The researchers narrowed it down to four cultivars that they recommend patients with anxiety should avoid. Four of the worst cultivars for treating anxiety include:
Remember that this was a small study in one dispensary in Canada, and one of these cannabis strains mentioned above may be actually wonderful for your anxiety! Learning what is best for your body, including what terpenes and cannabinoids it prefers, is important.
If your anxiety makes you paranoid, there’s a chance that cannabis can make this worse, and it won’t matter what strain you pick. This is why we always recommend going low and slow with cannabis medicine, especially when trying edibles.
As with any supplement or medication, results will vary from patient to patient. The above lists of cannabis strains to try and cannabis strains to avoid for anxiety might surprise some of our readers who find that some of the cultivars work for them, and vice versa. Always discuss with your doctor whether treating your anxiety with cannabis is a healthy option. Always experiment and consume responsibly.
As research on cannabis medicine progresses, we will see more of these studies done. The results of these studies will tell us which cultivars, cannabinoids, and terpenes best treat conditions like anxiety, and bring some much-needed relief to those of us who live with them.
HashDash guides are for educational and entertainment purposes only. This article is not intended to diagnose, treat, or cure anxiety disorders or any other conditions.
Millions of people suffer from anxiety. Fortunately, cannabis may help. Here’s what else we learned in this chapter:
We’re close to the halfway point of our Cannabis and the Body guide! If you’re ready to learn more, answer the question below and let’s keep it moving.
Only high-THC cultivars can help with anxiety.

Dr. Michele Ross
Dr. Michele Ross is a serial entrepreneur and the founder of Infused Partners, a digital health consulting firm and plant medicine incubator. She has served on the medical advisory boards of many companies in the cannabis and wellness spaces and holds a PhD in Neuroscience as well as an Executive MBA.
She has authored 5 books including Kratom Is Medicine, Vitamin Weed, CBD Oil For Health, and Train Your Brain To Get Thin. As both a patient with chronic illness and a clinician, she has advocated for drug policy reform for over a decade. She founded the first 501c3 nonprofit research institute on cannabis and women's health. Dr. Ross was a founding member of the team that decriminalized psilocybin mushrooms in Denver, the first city in the US to do so. She is also a psychedelic guide and integration coach.
Dr. Ross is known for breaking boundaries as the first scientist to star on a reality television series in the world, finishing 4th place on the hit CBS series Big Brother 11. She has been featured on the Today Show, The Doctors, Vice, and many other media outlets, and now lives in Las Vegas.